Improving outcomes for sarcoma patients through subtype-specific NCI trials
Official title: Improving Patient Outcomes Through Subtype Specific NCI-Sponsored Sarcoma Clinical Trials
Funded at Mayo Clinic Rochester · NIH-11447867 · Data updated 2026-11-12
A Mayo Clinic-led effort to run and complete targeted sarcoma clinical trials that focus on specific histologic subtypes to better tailor treatment for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 4, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $207,179 |
| NIH project number | 1R50CA305003-01A1 |
| Project ID | NIH-11447867 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with sarcoma, particularly those with histologic subtypes like liposarcoma, leiomyosarcoma, undifferentiated pleomorphic sarcoma, dedifferentiated liposarcoma, or angiosarcoma, who may be eligible for ongoing or future subtype-specific trials.
✕Less likely to help
Patients not eligible for current or upcoming sarcoma subtype trials or those with non-sarcoma cancers would not directly benefit from this grant.
What this research studies
This grant supports continuing and coordinating subtype-focused clinical trials for sarcoma, with emphasis on biomarker analyses and translating results into practice. It involves collaboration across Mayo Clinic and allied groups to generate new trial concepts, activate protocols, and improve patient accrual to sarcoma trials. The work includes drafting abstracts and manuscripts and leveraging correlative studies to inform future treatment strategies for people with sarcoma. The goal is to move promising subtype-specific treatments from trial concepts toward real-world care for patients with sarcoma.
Why it matters
Potential benefit: Patients with sarcoma could receive more personalized, subtype-tailored treatment options based on trial findings and biomarker insights.
How similar studies have gone: Prior NCI/NCTN trials in sarcoma have shown that histologic subtype-focused strategies can yield meaningful signals and guide future therapies, though results can be variable by subtype.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Robinson, Steven — Mayo Clinic Rochester
- Study coordinator: Robinson, Steven
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.