Improving imaging techniques for identifying brain tissue at risk during strokes
Hyperpolarized 13C metabolic imaging in an endovascular swine model of ischemic stroke
This study is testing a new imaging method to help doctors find brain tissue that can still be saved during a stroke, which could lead to better treatment options for patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10932974 on NIH RePORTER |
What this research studies
This research investigates a new imaging technique using hyperpolarized 13C metabolic imaging to better identify brain tissue that is at risk during ischemic strokes. By using an endovascular swine model, the study aims to enhance the accuracy of detecting salvageable brain tissue, known as the penumbra, which is crucial for timely intervention. The approach focuses on understanding energy metabolism changes in the brain following a stroke, which could lead to improved treatment strategies. Patients may benefit from more precise assessments that could expand eligibility for life-saving therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced an ischemic stroke and are within the critical time window for treatment.
Not a fit: Patients who have suffered from hemorrhagic strokes or those outside the treatment window may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for stroke patients by accurately identifying brain tissue that can still be saved.
How similar studies have performed: Previous studies have shown promise in improving imaging techniques for stroke assessment, but this specific approach using hyperpolarized 13C is relatively novel.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Mayer, Dirk — University of Maryland Baltimore
- Study coordinator: Mayer, Dirk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.