NIH-funded research NIH-funded research

Improving health outcomes for older adults with osteoarthritis and multiple health conditions

Official title: Improving health outcomes in older patients with osteoarthritis and multimorbidity

Funded at Dartmouth-Hitchcock Clinic · NIH-11265893 · Data updated 2026-11-12

Aimed at helping adults over 21 with osteoarthritis and other chronic health issues improve how they feel and function through better activity, weight management, and overall care.

More Osteoarthritis research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDartmouth-Hitchcock Clinic
NIH-funded
Lab location1 site (Lebanon, United States)
Project startJune 18, 2026
Project endMarch 31, 2031
Funding year2026
Award (this year)$217,130
NIH project number1P20GM161873-01
Project IDNIH-11265893 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older with osteoarthritis and additional health conditions who are engaged in or eligible for physical activity and weight-management programs.

Less likely to help

Patients without access to programs or who have medical contraindications to exercise may not benefit.

What this research studies

This project focuses on older adults who have osteoarthritis in addition to other health problems, and how to improve their daily living and medical outcomes. It emphasizes physical activity, exercise, and weight management as core strategies to reduce pain and improve health. Researchers plan to translate and implement effective approaches into real-world care to help patients stay active and manage multiple conditions better. The work is conducted in collaboration with Dartmouth-Hitchcock Clinic, led by a clinician-researcher team to address practical needs of patients and providers. The goal is to create practical, scalable pathways that reduce disability and improve longevity for this high-risk population.

Why it matters

Potential benefit: If successful, patients could experience less pain, improved mobility, and better control of obesity, diabetes, and heart disease through feasible exercise and weight-management strategies.

How similar studies have gone: Prior research supports physical activity and weight management for OA and comorbidities, but this project aims to enhance real-world uptake and outcomes in an older population.

Where this research is happening

  • Dartmouth-Hitchcock Clinic
    Lebanon, United States
    Active

Researchers

  • Principal investigator: Macfarlane, Lindsey a. — Dartmouth-Hitchcock Clinic
  • Study coordinator: Macfarlane, Lindsey a.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.