NIH-funded research R01 grant

Improving cognitive function in breast cancer survivors through computerized training

Official title: Cognitive Training for Cancer-related Cognitive Impairment: A Multi-Center Randomized Controlled Trial

Funded at Ohio State University · NIH-11030332 · Data updated 2026-11-12

This study is looking at whether fun brain training exercises can help breast cancer survivors who are having trouble with their thinking and memory after treatment, to see if it can make them feel better and improve their daily lives.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startFebruary 15, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$534,903
NIH project number5R01CA276222-03
Project IDNIH-11030332 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are breast cancer survivors experiencing cognitive impairment following their treatment.

Less likely to help

Patients who have not undergone cancer treatment or those without cognitive impairment may not benefit from this research.

What this research studies

This research investigates the effectiveness of computerized cognitive training for breast cancer survivors who are experiencing cognitive impairment related to their cancer treatment. The study will involve a randomized controlled trial where participants will engage in cognitive training exercises designed to enhance brain function. By comparing this training to an active attention control group, the research aims to determine if these exercises can significantly improve cognitive abilities and overall quality of life for survivors. The approach is grounded in the principles of neuroplasticity, which suggests that the brain can reorganize itself and form new neural connections.

Why it matters

Potential benefit: If successful, this research could lead to effective interventions that improve cognitive function and quality of life for breast cancer survivors.

How similar studies have gone: Previous pilot studies have shown promise for similar cognitive training approaches, but this trial aims to provide more robust evidence through a larger, controlled design.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Von Ah, Diane Marie — Ohio State University
  • Study coordinator: Von Ah, Diane Marie

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.