Improving care for people with opioid use disorder
Official title: The OUD Cascade of Care and Critical Outcomes: Longitudinal Linkage with Opioid Use
Funded at New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-10741268 · Data updated 2026-11-12
This study is looking at how to improve access to and success in treatment for people dealing with opioid use disorder, especially by understanding how things like the availability of fentanyl affect their recovery and safety, so we can create better support that fits their changing needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | June 15, 2023 |
| Project end | March 31, 2030 |
| Funding year | 2023 |
| Award (this year) | $710,671 |
| NIH project number | 1R01DA059042-01 |
| Project ID | NIH-10741268 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with opioid use disorder who are currently receiving or seeking medication-assisted treatment.
✕Less likely to help
Patients who are not diagnosed with opioid use disorder or those who are not engaged in any form of treatment may not benefit from this research.
What this research studies
This research investigates how to enhance access to and retention in effective treatment for opioid use disorder (OUD) by examining the stages of care under the OUD Cascade of Care framework. It focuses on the impact of local drug supply conditions, particularly fentanyl prevalence, on treatment outcomes. The study aims to understand how ongoing opioid use affects treatment engagement and the risks of overdose, while also exploring the protective effects of long-term buprenorphine treatment. By analyzing these factors over time, the research seeks to develop tailored harm reduction strategies that align with patients' evolving goals.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that reduce overdose risks and enhance the effectiveness of care for individuals with opioid use disorder.
How similar studies have gone: Other research has shown success in using the Cascade of Care framework to improve treatment outcomes for opioid use disorder, though this study's focus on local drug supply dynamics is relatively novel.
Where this research is happening
-
New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
New York, United States Active
Researchers
- Principal investigator: Williams, Arthur R — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Williams, Arthur R
Related research
Other NIH-funded projects on the same topics.
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Systems analysis to improve opioid use disorder care after jail release (SAIA-MOUD)
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This project helps unhoused people in Montana get life-saving medicines for opioid use disorder through clinics connected to syringe service programs, a nurse-led MOUD model, and peer support.
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Optimizing long-acting PrEP and opioid treatment for people in jails and prisons
This project tests a real-world approach to using long-acting PrEP and buprenorphine for HIV prevention and opioid treatment among incarcerated individuals and after release.
-
Scaling up medications for opioid use disorder in residential treatment programs
This grant studies how to help residential treatment programs provide medications for opioid use disorder to reduce overdoses after discharge, focusing on real-world settings and policies.
-
Increasing Capacity at a Native Community Clinic to Improve Opioid Care for urban AI/AN
This grant helps a Native American health clinic build its research capacity to better serve urban American Indian and Alaska Native people dealing with opioid use disorder and related health issues.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.