Improving care for people with opioid use disorder

The OUD Cascade of Care and Critical Outcomes: Longitudinal Linkage with Opioid Use

NIH-funded research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-10741268

This study is looking at how to improve access to and success in treatment for people dealing with opioid use disorder, especially by understanding how things like the availability of fentanyl affect their recovery and safety, so we can create better support that fits their changing needs.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10741268 on NIH RePORTER

What this research studies

This research investigates how to enhance access to and retention in effective treatment for opioid use disorder (OUD) by examining the stages of care under the OUD Cascade of Care framework. It focuses on the impact of local drug supply conditions, particularly fentanyl prevalence, on treatment outcomes. The study aims to understand how ongoing opioid use affects treatment engagement and the risks of overdose, while also exploring the protective effects of long-term buprenorphine treatment. By analyzing these factors over time, the research seeks to develop tailored harm reduction strategies that align with patients' evolving goals.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with opioid use disorder who are currently receiving or seeking medication-assisted treatment.

Not a fit: Patients who are not diagnosed with opioid use disorder or those who are not engaged in any form of treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies that reduce overdose risks and enhance the effectiveness of care for individuals with opioid use disorder.

How similar studies have performed: Other research has shown success in using the Cascade of Care framework to improve treatment outcomes for opioid use disorder, though this study's focus on local drug supply dynamics is relatively novel.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.