Improved Lung Cancer Screening for People Living with HIV
Official title: Improved Lung Cancer Screening Approaches for People Living with HIV
Funded at Icahn School of Medicine at Mount Sinai · NIH-11328395 · Data updated 2026-11-12
A new plan to find the best way to screen for lung cancer in people living with HIV so they can be diagnosed earlier when treatment is more likely to help.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2026 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $711,272 |
| NIH project number | 1R01CA310749-01 |
| Project ID | NIH-11328395 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults living with HIV who have a high-risk smoking history and are eligible for lung cancer screening.
✕Less likely to help
People without HIV, with low smoking risk, or who do not meet screening guidelines may not benefit.
What this research studies
This project focuses on figuring out the most effective lung cancer screening approach for people with HIV, a group at higher risk and with different health considerations. Researchers will examine who should be screened, what tests to use, and how to interpret results to reduce false positives and ensure timely follow-up. The study considers factors unique to HIV, like immune status, and aims to tailor screening guidelines to improve early detection and minimize harms. Participants may contribute data, undergo screening tests, and have follow-up assessments as part of safer, personalized care planning.
Why it matters
Potential benefit: If successful, this work could lead to earlier lung cancer detection and better survival for people living with HIV.
How similar studies have gone: Previous screening trials in people without HIV showed benefits, but this study adapts methods to the HIV population where risks and screening outcomes differ.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Sigel, Keith Magnus — Icahn School of Medicine at Mount Sinai
- Study coordinator: Sigel, Keith Magnus
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-
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Personalized Lung Cancer Screening for Veterans
Aimed at improving who gets screened and how lung cancer is diagnosed among Veterans using personalized tools.
-
Proteogenomic framework to improve lung cancer screening with biomarkers
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.