Personalized Lung Cancer Screening for Veterans
Official title: Personalizing Veterans' Lung Cancer Screening and Diagnosis
Funded at Veterans Health Administration · NIH-11446454 · Data updated 2026-11-12
Aimed at improving who gets screened and how lung cancer is diagnosed among Veterans using personalized tools.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2027 |
| Funding year | 2027 |
| NIH project number | 5I01CX002686-03 |
| Project ID | NIH-11446454 on NIH RePORTER |
Who could benefit from this research
✓Could help
Veterans aged 50 to 80 who smoke or quit within the past 15 years and who may have additional exposure-related risk factors.
✕Less likely to help
Veterans who do not meet high-risk criteria or have non-lung cancer conditions may not benefit.
What this research studies
This project focuses on tailoring when and how Veterans are screened for lung cancer using LDCT, with an emphasis on including Veterans who may be at risk but don’t meet current eligibility. It proposes using new clues from biomarkers and an AI tool called LCP-CNN to better distinguish benign nodules from cancer, potentially speeding diagnosis. The plan addresses why current criteria miss a large share of cancers and how veteran-specific exposures might be used to refine screening decisions.
Why it matters
Potential benefit: If successful, Veterans could receive more accurate screening and faster, less invasive diagnoses.
How similar studies have gone: Prior lung cancer screening trials showed mortality reduction with LDCT, and AI approaches are emerging to improve nodule assessment.
Where this research is happening
-
Veterans Health Administration
Nashville, United States Active
Researchers
- Principal investigator: Lewis, Jennifer a — Veterans Health Administration
- Study coordinator: Lewis, Jennifer a
Related research
Other NIH-funded projects on the same topics.
-
Digital health strategies to expand lung cancer screening in safety-net clinics
A funded project aims to help low-resource clinics increase the use of lung cancer screening for patients who smoke or are at risk.
-
Integrated approach to lung screening and quitting for African Americans
A multi-level program aims to boost LDCT lung cancer screening uptake and help African American smokers quit, with support from a comprehensive community-focused plan.
-
Population health approach to boost lung cancer screening at community clinics
A large Utah project aims to help community clinics reach more eligible adults to get low-dose CT lung cancer screening.
-
Group-based tobacco treatment for older adults after lung cancer screening
A study tests a group-based tobacco cessation program for older adults who are getting lung cancer screening to help them quit smoking.
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Proteogenomic framework to improve lung cancer screening with biomarkers
A biomarker-based approach aims to refine LDCT lung cancer screening so more cancers are caught early while reducing unnecessary procedures.
-
Using quitlines to spread lung cancer screening information to people who smoke
A large cancer center project will test two ways of delivering lung cancer screening information to adults who smoke, using quitlines as a trusted channel to reach them.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.