IMPROVE-AKI: Team coaching to prevent kidney injury after heart catheterization
Official title: IMPROVE-AKI: A Cluster-Randomized Trial of Team-Based Coaching Interventions to IMPROVE Acute Kidney Injury
Funded at Dartmouth College · NIH-11366819 · Data updated 2026-11-12
A large study tests a team-based coaching program to help hospitals use proven practices that prevent kidney injury after heart catheter procedures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | July 15, 2018 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $1,501,740 |
| NIH project number | 2R01DK113201-06A1 |
| Project ID | NIH-11366819 on NIH RePORTER |
Who could benefit from this research
✓Could help
Hospitals and patients undergoing diagnostic or interventional cardiac catheterization in participating sites.
✕Less likely to help
Patients treated at non-participating sites or in settings where the implementation bundle is not adopted may not see direct benefits.
What this research studies
This project aims to spread and sustain proven practices to reduce acute kidney injury (AKI) after cardiac catheterization through a bundled, team-focused implementation approach. It builds on a previous trial that showed a 46% reduction in AKI with a Virtual Learning Collaborative and surveillance system, and now tests this scaling strategy across settings. The study uses a hybrid type III design to prioritize implementation success while also observing patient outcomes. Hospitals participate in structured coaching, monitoring, and feedback to ensure lasting use of EBIs that protect kidney function. Results could inform best practices for patient safety and reduce costly AKI events across care systems.
Why it matters
Potential benefit: If successful, this approach could significantly lower AKI rates after catheterization, improving survival and reducing healthcare costs.
How similar studies have gone: A prior trial demonstrated substantial AKI reduction and cost savings when using the bundled implementation approach.
Where this research is happening
-
Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Brown, Jeremiah R — Dartmouth College
- Study coordinator: Brown, Jeremiah R
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.