Identifying pediatric asthma subtypes with privacy-friendly federated learning
Official title: Identifying pediatric asthma subtypes using novel privacy-preserving federated machine learning methods
Funded at University of Florida · NIH-11372797 · Data updated 2026-11-12
A pediatric asthma study using privacy-preserving computer methods to find distinct asthma subtypes in children and tailor care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $695,667 |
| NIH project number | 5R01HL169277-04 |
| Project ID | NIH-11372797 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children aged 0-11 with asthma or suspected asthma, treated in participating healthcare networks.
✕Less likely to help
Children whose asthma does not fit the identified subtypes or who do not access care within participating networks may see limited benefit.
What this research studies
This project will use federated machine learning across large clinical networks to identify asthma subtypes in children aged 0-11 using real-world data while protecting patient privacy. Researchers will combine diverse data from multiple sites without sharing individual records to uncover patterns related to symptoms, triggers, and treatment responses. The goal is to help clinicians personalize primary and emergency care based on subtype, potentially reducing exacerbations and healthcare use.
Why it matters
Potential benefit: If successful, the work could lead to more precise, personalized care for children with asthma and fewer emergency visits and hospitalizations.
How similar studies have gone: Previous work suggests that pediatric asthma has subtypes; this study extends it with privacy-preserving, multi-site data, which is relatively novel.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Fishe, Jennifer Noel — University of Florida
- Study coordinator: Fishe, Jennifer Noel
Related research
Other NIH-funded projects on the same topics.
-
Predicting and Preventing Asthma Exacerbations in Children Exposed to Air Pollution
A pediatric-focused project aims to predict which kids with asthma are most at risk for flare-ups when air pollution is high, so clinicians can prevent attacks.
-
BPAP in severe pediatric asthma: a new treatment pathway for kids in the ED
A clinical trial tests whether starting BPAP, a non-invasive breathing support, in the emergency department helps kids with severe asthma recover faster and use fewer critical-care resources.
-
T-helper 2-low asthma in children: finding biomarkers and understanding triggers
A mentored, five-year career development grant aims to improve diagnosis and understand the causes of T2LOW asthma in children.
-
Positive Affect and Asthma in Kids: A New Way to Help Teens Stick to Their Inhalers
A study at Chapman University aims to help children and teens with asthma use their inhaled medications more consistently by using positive psychology approaches.
-
Air pollution sensitivity in pediatric asthma
Kids with asthma may have worse symptoms on days with dirty air, and this project aims to predict and prevent those flare-ups using data from medical records, genetics, and the environment.
-
Urban rat exposure and pediatric asthma in inner-city children
This grant explores whether living near rats affects how bad asthma is for children in urban areas.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.