Identifying brain-based markers for predicting psychosis risk
Identification of Distinct Biotypes in Clinical High Risk for Psychosis State Using Objective Brain-Based Biomarkers
This study is looking at how certain brain signals can help spot people who are at a higher risk of developing psychosis, so we can better understand their needs and provide the right support.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10772165 on NIH RePORTER |
What this research studies
This research investigates how distinct brain-based biomarkers can help identify individuals at clinical high risk for developing psychosis. By analyzing a variety of cognitive and electrophysiological data, the study aims to classify patients into specific biotypes that reflect their unique clinical trajectories. This approach seeks to improve predictions about who may develop psychosis and tailor interventions accordingly. Patients participating in this research may undergo assessments that include brain imaging and cognitive tests to gather comprehensive data.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals identified as being at clinical high risk for psychosis, which may include those with early symptoms or family histories of psychotic disorders.
Not a fit: Patients who are not at clinical high risk for psychosis or those with established psychotic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions and personalized treatment strategies for individuals at risk of psychosis.
How similar studies have performed: Previous research has shown promise in using neurobiological markers to predict psychosis risk, but this approach aims to refine and validate these methods further.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Yassine, Walid — Beth Israel Deaconess Medical Center
- Study coordinator: Yassine, Walid
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.