How platelets affect complications after ischemic stroke

Platelets as regulator of non-neurological complications of ischemic stroke

NIH-funded research Thomas Jefferson University · NIH-11049488

This study is looking at how platelets, which are tiny cells in your blood, can cause problems in other parts of your body after you've had an ischemic stroke, and it's hoping to find new ways to help stroke patients recover better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionThomas Jefferson University NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11049488 on NIH RePORTER

What this research studies

This research investigates the role of platelets in causing complications following ischemic stroke, which occurs when blood clots block blood flow to the brain. The study aims to understand how activated platelets can lead to damage in other organs, such as the lungs and intestines, after a stroke. By exploring the mechanisms of platelet activity, the research seeks to develop new therapies that could mitigate these complications and improve recovery outcomes for stroke patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced an ischemic stroke and are at risk for complications during recovery.

Not a fit: Patients who have not had a stroke or those with non-ischemic stroke types may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that reduce complications and improve recovery for stroke patients.

How similar studies have performed: While the role of platelets in stroke recovery is being explored, this specific approach to targeting platelet activity for reducing complications is relatively novel.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.