How breathing and swallowing coordination affects long-term swallowing problems after stroke
Official title: The Mechanistic Role of Respiratory-Swallow Coordination in Chronic Dysphagia Following Cortical Ischemic Stroke
Funded at Ohio State University · NIH-11354905 · Data updated 2026-11-12
This project looks at how the timing between breathing and swallowing may contribute to chronic swallowing problems in people who had an ischemic stroke.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | June 16, 2026 |
| Project end | June 15, 2028 |
| Funding year | 2026 |
| Award (this year) | $315,000 |
| NIH project number | 1R03HD122223-01 |
| Project ID | NIH-11354905 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years or older with chronic dysphagia after ischemic stroke.
✕Less likely to help
Individuals without chronic post-stroke dysphagia or those without respiratory-swallow coordination issues may not benefit.
What this research studies
After stroke, many people develop chronic dysphagia that can lead to pneumonia and other serious health issues. The study aims to map how breathing and swallowing are coordinated in adults with chronic post-stroke dysphagia and see how these patterns relate to swallowing safety and efficiency. Researchers will analyze physiological swallowing measures and patient-centered outcomes to identify mechanisms behind persistent dysphagia. The goal is to inform the development of targeted interventions that could improve swallowing and reduce related complications.
Why it matters
Potential benefit: If successful, the work could lead to new therapies that improve swallowing safety and quality of life for stroke survivors with chronic dysphagia.
How similar studies have gone: Prior research suggests a link between respiratory-swallow coordination and swallowing outcomes, supporting the potential value of this approach.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Kantarcigil, Cagla — Ohio State University
- Study coordinator: Kantarcigil, Cagla
Related research
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-
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-
Genetic testing to find causes of early-onset ischemic stroke
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-
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This project looks at whether measures of biological aging and patterns of blood proteins help explain which stroke survivors keep their thinking sharp and which go on to develop vascular dementia.
-
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.