HIV prevention network and operations center

HIV Prevention Trials Network Leadership and Operations Center

NIH-funded research Family Health International · NIH-11466552

This program develops and runs new HIV prevention tools—like long‑acting medicines, combined HIV/contraception products, and antibodies—for people at higher risk such as young adults, women in sub‑Saharan Africa, men who have sex with men, transgender women, sex workers, and people who inject drugs.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionFamily Health International NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11466552 on NIH RePORTER

What this research studies

From my point of view, this network brings together researchers, clinics, and communities to design and run clinical studies of promising HIV prevention options. They test long‑acting antiretroviral medicines for PrEP, multipurpose products that could prevent HIV and pregnancy or STIs, and antibody‑based approaches, tailoring studies to groups at higher risk. Studies are carried out at sites in the U.S. and around the world, with attention to safety monitoring, community engagement, and making successful tools scalable. The operations center coordinates study logistics, data management, and partnerships with other networks to speed up testing and delivery of effective interventions.

Who could benefit from this research

Good fit: Ideal participants are people at increased risk of acquiring HIV—including young men and women, women in sub‑Saharan Africa, men who have sex with men, transgender women who have sex with men, sex workers, and people who inject drugs—who live near a participating site and are willing to try study prevention products.

Not a fit: People who are not at risk for HIV, those already living with HIV (unless a specific sub‑study includes them), or individuals unable or unwilling to attend a study site are unlikely to benefit from participating.

Why it matters

Potential benefit: If successful, this work could lower new HIV infections by making prevention safer, longer‑lasting, and easier to use for people at risk.

How similar studies have performed: Some prevention approaches like daily oral PrEP and injectable long‑acting PrEP have already reduced HIV risk, while multipurpose products and antibody strategies are newer and still being tested for effectiveness.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.