HIV prevention network and operations center
Official title: HIV Prevention Trials Network Leadership and Operations Center
Funded at Family Health International · NIH-11466552 · Data updated 2026-11-12
This program develops and runs new HIV prevention tools—like long‑acting medicines, combined HIV/contraception products, and antibodies—for people at higher risk such as young adults, women in sub‑Saharan Africa, men who have sex with men, transgender women, sex workers, and people who inject drugs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Family Health International NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | June 1, 2006 |
| Project end | November 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $10,000 |
| NIH project number | 3UM1AI068619-20S2 |
| Project ID | NIH-11466552 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are people at increased risk of acquiring HIV—including young men and women, women in sub‑Saharan Africa, men who have sex with men, transgender women who have sex with men, sex workers, and people who inject drugs—who live near a participating site and are willing to try study prevention products.
✕Less likely to help
People who are not at risk for HIV, those already living with HIV (unless a specific sub‑study includes them), or individuals unable or unwilling to attend a study site are unlikely to benefit from participating.
What this research studies
From my point of view, this network brings together researchers, clinics, and communities to design and run clinical studies of promising HIV prevention options. They test long‑acting antiretroviral medicines for PrEP, multipurpose products that could prevent HIV and pregnancy or STIs, and antibody‑based approaches, tailoring studies to groups at higher risk. Studies are carried out at sites in the U.S. and around the world, with attention to safety monitoring, community engagement, and making successful tools scalable. The operations center coordinates study logistics, data management, and partnerships with other networks to speed up testing and delivery of effective interventions.
Why it matters
Potential benefit: If successful, this work could lower new HIV infections by making prevention safer, longer‑lasting, and easier to use for people at risk.
How similar studies have gone: Some prevention approaches like daily oral PrEP and injectable long‑acting PrEP have already reduced HIV risk, while multipurpose products and antibody strategies are newer and still being tested for effectiveness.
Where this research is happening
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Family Health International
Durham, United States Active
Researchers
- Principal investigator: Landovitz, Raphael J — Family Health International
- Study coordinator: Landovitz, Raphael J
Related research
Other NIH-funded projects on the same topics.
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Making HIV prevention and care easier for Ugandan youth
A Ugandan study is testing ways to help adolescents and young adults (15–24) prevent HIV and stay healthy, using long-acting PrEP and youth-friendly services.
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Innovative HIV Prevention and Care Interventions for Adolescents and Young Adults in Uganda
A Ugandan research team is testing practical, youth-focused strategies to help 15-24 year-olds using HIV prevention or treatment services stay healthy and engaged in care.
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Adolescent girls in Uganda: a long-term look at how money empowerment and family support affect HIV prevention, care, and mental health
A long-term study in rural Uganda will test whether an intervention that combines economic empowerment and family strengthening can help HIV-negative and HIV-affected adolescent girls move safely into young adulthood.
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Long-term HIV prevention and mental health support for adolescent girls and young women in Uganda
A long-term program in rural Uganda tests if combining economic support and family strengthening helps teenage girls stay HIV-free and improve mental health as they grow into young adults.
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Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.