NIH-funded research R01 grant

Investigating the links between HIV, gestational diabetes, and tuberculosis in pregnant women

Official title: HIV, gestational diabetes and TB in pregnancy

Funded at Weill Medical Coll of Cornell Univ · NIH-10869955 · Data updated 2026-11-12

This study is looking at how HIV and gestational diabetes might increase the risk of tuberculosis in pregnant women, and it’s for expectant moms in their second trimester who want to understand more about their health during pregnancy.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWeill Medical Coll of Cornell Univ
NIH-funded
Lab location1 site (New York, United States)
Project startJuly 15, 2022
Project endJune 30, 2027
Funding year2024
Award (this year)$687,723
NIH project number5R01AI162235-03
Project IDNIH-10869955 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are pregnant women in their second trimester who are living with HIV and may also be at risk for gestational diabetes.

Less likely to help

Patients who are not pregnant or those without HIV or gestational diabetes may not benefit from this research.

What this research studies

This research focuses on understanding how HIV and gestational diabetes mellitus (GDM) affect the risk of tuberculosis (TB) in pregnant women. It aims to identify immune impairments that increase TB risk among women living with HIV, despite their use of combined anti-retroviral therapy. The study will involve enrolling pregnant women in their second trimester at a medical college in India, with follow-up visits throughout their pregnancy and postpartum period to monitor health outcomes. By examining the interactions between these conditions, the research seeks to provide insights into improving maternal health.

Why it matters

Potential benefit: If successful, this research could lead to better prevention and treatment strategies for TB in pregnant women with HIV, ultimately reducing maternal mortality.

How similar studies have gone: Previous research has shown significant associations between HIV, diabetes, and TB in non-pregnant populations, suggesting that this approach may yield valuable insights.

Where this research is happening

  • Weill Medical Coll of Cornell Univ
    New York, United States
    Active

Researchers

  • Principal investigator: Mathad, Jyoti S — Weill Medical Coll of Cornell Univ
  • Study coordinator: Mathad, Jyoti S

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.