Investigating the links between HIV, gestational diabetes, and tuberculosis in pregnant women
HIV, gestational diabetes and TB in pregnancy
This study is looking at how HIV and gestational diabetes might increase the risk of tuberculosis in pregnant women, and it’s for expectant moms in their second trimester who want to understand more about their health during pregnancy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10869955 on NIH RePORTER |
What this research studies
This research focuses on understanding how HIV and gestational diabetes mellitus (GDM) affect the risk of tuberculosis (TB) in pregnant women. It aims to identify immune impairments that increase TB risk among women living with HIV, despite their use of combined anti-retroviral therapy. The study will involve enrolling pregnant women in their second trimester at a medical college in India, with follow-up visits throughout their pregnancy and postpartum period to monitor health outcomes. By examining the interactions between these conditions, the research seeks to provide insights into improving maternal health.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women in their second trimester who are living with HIV and may also be at risk for gestational diabetes.
Not a fit: Patients who are not pregnant or those without HIV or gestational diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for TB in pregnant women with HIV, ultimately reducing maternal mortality.
How similar studies have performed: Previous research has shown significant associations between HIV, diabetes, and TB in non-pregnant populations, suggesting that this approach may yield valuable insights.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Mathad, Jyoti S — Weill Medical Coll of Cornell Univ
- Study coordinator: Mathad, Jyoti S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.