Genetic and genomic clues to lactation disorders in mothers
Official title: Investigating the genetic and genomic mechanisms of human lactation disorders
Funded at Icahn School of Medicine at Mount Sinai · NIH-11366592 · Data updated 2026-11-12
Researchers are studying how genetics influence why some mothers have trouble producing enough milk, which can affect babies and families.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | June 1, 2026 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $751,204 |
| NIH project number | 1R01HD119172-01A1 |
| Project ID | NIH-11366592 on NIH RePORTER |
Who could benefit from this research
✓Could help
Parents experiencing lactation difficulties, especially those with reduced milk production or secretion.
✕Less likely to help
Mothers without lactation issues or those not seeking genetic insights may not benefit directly.
What this research studies
This project from Mount Sinai will look at how genetic differences in mothers relate to common lactation problems like agalactia and hypogalactia. By examining genetic and genomic data, scientists aim to uncover biological pathways that control milk production. The study could eventually lead to better support, diagnosis, and treatments for mothers facing lactation challenges. The goal is to improve breastfeeding outcomes and infant health by understanding the biology behind lactation disorders from a maternal perspective.
Why it matters
Potential benefit: If successful, this work could lead to new tests and personalized interventions to help mothers produce sufficient milk.
How similar studies have gone: Previous work has linked genetics to milk production, but the exact genetic mechanisms remain largely unknown, making this approach novel in parts.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Itan, Yuval — Icahn School of Medicine at Mount Sinai
- Study coordinator: Itan, Yuval
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.