Food allergy data hub
Official title: Bioinformatics Core
Funded at Food Allergy Science Initiative, INC. · NIH-11322739 · Data updated 2026-11-12
A centralized team will build online tools to analyze genetic and imaging data to help researchers studying food allergies and the people they treat.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Food Allergy Science Initiative, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | May 14, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $145,985 |
| NIH project number | 5P01AI179273-03 |
| Project ID | NIH-11322739 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with diagnosed food allergies who are willing to provide biological samples or join related research studies (children and adults as allowed by each site).
✕Less likely to help
People without food allergies or whose condition does not involve the gut, immune, or neuronal pathways under study are unlikely to receive direct benefit.
What this research studies
This project will create a central bioinformatics team that analyzes sequencing and imaging data collected for food allergy research. They will process transcriptomes from gut epithelial, neuronal, and immune cells and analyze specialized uLIPSTIC imaging data. The team will set up high-throughput analysis pipelines and easy web tools so researchers can explore, compare, and share results. They will also work with partner labs to standardize best practices for analyzing the imaging and sequencing data.
Why it matters
Potential benefit: If successful, this could speed discovery of biological markers and treatment targets that lead to better tests and therapies for food allergies.
How similar studies have gone: Other bioinformatics cores and shared data platforms have helped researchers make discoveries in allergy and immune research, so this approach builds on proven methods.
Where this research is happening
-
Food Allergy Science Initiative, INC.
Cambridge, United States Active
Researchers
- Principal investigator: Carroll, Thomas S — Food Allergy Science Initiative, INC.
- Study coordinator: Carroll, Thomas S
Related research
Other NIH-funded projects on the same topics.
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How gut nerves and immune cells interact in food allergy
This project looks at how contacts between gut nerves, immune cells, and hormone-producing gut cells affect allergic reactions to food for people with food allergies.
-
How mast cells trigger gut lining and nerve responses in food allergy
This project looks at how immune cells called mast cells change the gut lining and nerves in people with food allergies.
-
How nerves and the immune system cause food allergy symptoms
This project explores how nerves and the immune system cause the symptoms people with food allergies feel, like nausea, breathing changes, and low blood pressure.
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Custom genetically engineered mice for food allergy
This program creates specially modified mice to help scientists better understand and develop treatments for food allergies.
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How the nerves and immune system affect food allergies
Researchers are looking at how the nervous system and immune system interact in people with food allergies to find better ways to prevent and treat reactions.
-
Investigating how nerve and immune cells interact during food allergies
This study is looking at how nerve and immune cells in the gut work together when someone has a food allergy, hoping to find new ways to help manage and treat these allergies so that patients can better understand their reactions and feel better.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.