Investigating how nerve and immune cells interact during food allergies
Official title: Project 3: Physical neuro-immune interactions during food allergy
Funded at Food Allergy Science Initiative, INC. · NIH-11088835 · Data updated 2026-11-12
This study is looking at how nerve and immune cells in the gut work together when someone has a food allergy, hoping to find new ways to help manage and treat these allergies so that patients can better understand their reactions and feel better.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Food Allergy Science Initiative, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | May 14, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $593,250 |
| NIH project number | 5P01AI179273-02 |
| Project ID | NIH-11088835 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with diagnosed food allergies or those experiencing allergic reactions to specific foods.
✕Less likely to help
Patients without food allergies or those who do not experience allergic reactions to foods may not benefit from this research.
What this research studies
This research explores the complex interactions between nerve cells and immune cells in the gastrointestinal tract, particularly in the context of food allergies. By examining how these cells communicate during both the sensitization phase and the allergic response, the study aims to uncover mechanisms that could influence the severity of food allergies. The research employs advanced techniques to analyze cellular changes and interactions in the gut, which may lead to new insights into food allergy management and treatment. Patients may benefit from a better understanding of how their bodies react to allergens and potential new therapeutic approaches.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and management strategies for individuals suffering from food allergies.
How similar studies have gone: Previous research has shown promising results in understanding neuro-immune interactions in other allergic conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Food Allergy Science Initiative, INC.
Cambridge, United States Active
Researchers
- Principal investigator: Mucida, Daniel S — Food Allergy Science Initiative, INC.
- Study coordinator: Mucida, Daniel S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.