NIH-funded research R21 grant

Feasibility of an AI-Driven Gait Freeze Detector to Trigger Pauses and Cues in Parkinson’s

Official title: Feasibility of a Novel Freezing of Gait Detection Framework for Adaptive Cueing in Parkinson's Disease

Funded at Case Western Reserve University · NIH-11354931 · Data updated 2026-11-12

A small study tests an AI system that detects when a person with Parkinson’s is about to freeze and gives a cue only at that moment to help them keep walking.

More s Disease research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionCase Western Reserve University
NIH-funded
Lab location1 site (Cleveland, United States)
Project startAugust 18, 2026
Project endMay 31, 2029
Funding year2026
Award (this year)$218,869
NIH project number1R21EB039456-01
Project IDNIH-11354931 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 and older with Parkinson’s disease who experience freezing of gait.

Less likely to help

Those without Parkinson’s or without FoG symptoms are unlikely to benefit.

What this research studies

If you have Parkinson’s and struggle with freezing of gait, this study explores a smart, wearable system that uses sensors and eye-tracking to detect FoG and provide timely cues. Researchers will train a model with high-quality sensor data and synthetic samples to improve accuracy in real-world settings. They will also examine how eye-related signals (gaze, blinks, pupil size) can boost detection and reduce false alarms when someone momentarily stops to adjust their step. The project is exploratory and aims to show whether this approach is feasible before larger trials.

Why it matters

Potential benefit: If successful, the system could help people with Parkinson’s stay mobile and reduce fall risk by delivering cues exactly when they are needed.

How similar studies have gone: Previous FoG detectors exist but often struggle with accuracy and real-world use; this study tests a potentially more robust approach.

Where this research is happening

  • Case Western Reserve University
    Cleveland, United States
    Active

Researchers

  • Principal investigator: Pulliam, Christopher Lee — Case Western Reserve University
  • Study coordinator: Pulliam, Christopher Lee

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.