NIH-funded research R01 grant

Faster, better-coordinated stroke care for rural communities

Official title: Regionalization of Acute Stroke Care for Rural Populations: A Systems Modeling Approach

Funded at Duke University · NIH-11289361 · Data updated 2026-11-12

This project uses computer models to find smarter ways for emergency responders and hospitals to get faster stroke treatment to people in rural areas.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startJuly 7, 2023
Project endJanuary 31, 2028
Funding year2026
Award (this year)$506,223
NIH project number7R01MD018031-04
Project IDNIH-11289361 on NIH RePORTER

Who could benefit from this research

Could help

This work is focused on people living in rural U.S. communities who might experience an acute stroke and the EMS/hospitals that care for them, rather than enrolling individual patients directly.

Less likely to help

Patients already served quickly by nearby comprehensive stroke centers or those not affected by acute ischemic stroke may see little direct benefit from this systems-level work.

What this research studies

If you live in a rural area and are at risk for stroke, this work looks at how emergency medical services (EMS), local hospitals, and specialized stroke centers can work together to shorten time to treatment. The team builds a decision-analytic systems model that combines real-world data on EMS routing, hospital capabilities, transfer times, and patient outcomes. They run many virtual scenarios to compare different EMS triage and transport strategies and how those choices affect access to clot-busting and clot-removing treatments. The results aim to guide regional planners and health systems on which system designs could save more lives and reduce long-term disability.

Why it matters

Potential benefit: If successful, this could lead to faster treatment and fewer deaths or disabilities from stroke for people in underserved rural areas.

How similar studies have gone: Previous programs that routed suspected stroke patients directly to stroke centers have reduced treatment delays, but the best triage and transport strategies across diverse rural regions remain unproven.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Patel, Mehul D. — Duke University
  • Study coordinator: Patel, Mehul D.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.