Exosome Production and Analysis Core Supporting Cardiovascular and Aging Research
Official title: Core B
Funded at Temple Univ of the Commonwealth · NIH-11387605 · Data updated 2026-11-12
A core facility helps scientists grow, isolate, and study exosomes from cell cultures and human samples to advance aging and heart disease research.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2017 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $388,606 |
| NIH project number | 5P01HL134608-08 |
| Project ID | NIH-11387605 on NIH RePORTER |
Who could benefit from this research
✓Could help
Researchers studying aging or cardiovascular disease who need exosome-based analyses and content profiling can access the core.
✕Less likely to help
Direct patient participation is not described; the core supports research rather than enrolling patients.
What this research studies
This core provides specialized services to generate exosomes, isolate them, and analyze their contents using molecular methods and bioinformatics. It supports projects across aging and cardiovascular biology by using samples from cell supernatants and both mouse and human plasma. The core is housed within Temple University’s Aging+ Cardiovascular Discovery Center and includes production and molecular analysis units, staffed to support multiple projects and collaborations. Researchers can access high-quality, standardized exosome workflows to accelerate discoveries relevant to human health.
Why it matters
Potential benefit: If successful, the core could enable faster, more reliable discovery of exosome roles in aging and cardiovascular disease, potentially guiding new diagnostics or therapies.
How similar studies have gone: Exosome research has shown promising insights in intercellular communication and disease biomarkers, suggesting potential for impactful findings.
Where this research is happening
-
Temple Univ of the Commonwealth
Philadelphia, United States Active
Researchers
- Principal investigator: Kishore, Raj — Temple Univ of the Commonwealth
- Study coordinator: Kishore, Raj
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.