Evaluating new oral tablets that release medication over time
Official title: Evaluation of Oral Modified-Release Tablets to Support the Approval of Additional Strengths
Funded at Northeastern University · NIH-10918252 · Data updated 2026-11-12
This study is all about creating special tablets that release medicine slowly and steadily to help people feel better and make it easier for them to take their medication, and it’s for anyone who needs a more effective way to manage their health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northeastern University NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $250,000 |
| NIH project number | 5U01FD007959-03 |
| Project ID | NIH-10918252 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would be patients who require oral medications that benefit from controlled release formulations.
✕Less likely to help
Patients who do not take oral medications or those who require immediate-release formulations may not benefit from this research.
What this research studies
This research focuses on developing oral modified-release (MR) tablets that can release medication at controlled rates to improve therapeutic effects and patient compliance. The study aims to identify key formulation variables that affect how these tablets work, using advanced testing and modeling techniques. By understanding these factors, the researchers hope to create additional strengths of these tablets that are safe and effective for patients. The project will also utilize machine learning to analyze data from existing MR products to enhance the formulation process.
Why it matters
Potential benefit: If successful, this research could lead to more effective oral medications with fewer side effects and improved patient adherence to treatment regimens.
How similar studies have gone: Previous research has shown promise in developing modified-release formulations, indicating that this approach has potential for success.
Where this research is happening
-
Northeastern University
Boston, United States Active
Researchers
- Principal investigator: Shen, Jie — Northeastern University
- Study coordinator: Shen, Jie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.