Enhancing MST with MY-SCOPE and machine learning to study in-session communication
Official title: Enhancing Multisystemic Therapy (MST) Effectiveness: A Novel Approach Using MY-SCOPE and Machine Learning for Within Session Communication Analysis
Funded at Case Western Reserve University · NIH-11523058 · Data updated 2026-11-12
A project to make Multisystemic Therapy more effective for teens with serious behavior problems by using a new tool called MY-SCOPE and machine learning to analyze what happens during therapy sessions.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | April 14, 2026 |
| Project end | September 15, 2027 |
| Funding year | 2025 |
| Award (this year) | $403,365 |
| NIH project number | 7R21MH137718-02 |
| Project ID | NIH-11523058 on NIH RePORTER |
Who could benefit from this research
✓Could help
Teens with serious externalizing problems and their families who are receiving or could receive Multisystemic Therapy.
✕Less likely to help
Teens not engaged in MST or those in settings where MST is not used may not benefit.
What this research studies
This grant aims to help adolescents with serious externalizing problems receive more effective family-based treatment in real-world settings. Researchers will explore how within-session communication patterns relate to therapy outcomes using MY-SCOPE and ML methods. The study focuses on translating evidence-based MST into practice while aiming to improve fidelity and effectiveness for underserved families. The work will be conducted in community-like settings associated with CASE Western Reserve University. Results could inform clinicians and programs on how to better support high-risk youth and their families.
Why it matters
Potential benefit: If successful, this approach could improve the effectiveness of MST for at-risk adolescents and help families achieve better outcomes.
How similar studies have gone: Prior MST research shows large benefits in controlled settings but real-world effectiveness varies; this project tests a novel implementation approach in real practice.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Ryan-Pettes, Stacy Renee — Case Western Reserve University
- Study coordinator: Ryan-Pettes, Stacy Renee
Related research
Other NIH-funded projects on the same topics.
-
Estrogen signaling and how the intestinal lining protects against injury
A study at Case Western Reserve University looks at how estrogen receptors in the gut lining help protect against intestinal injury and inflammatory bowel disease.
-
Diabetes: Long-term effects of intensive glucose control on complications
A long-term study follows adults with type 1 diabetes to see how keeping blood sugar close to normal affects eye, kidney, nerve, heart, and quality of life outcomes over many years.
-
Epidemiology of Diabetes Interventions and Complications (EDIC) Study follow-up
This long-term study follows adults with type 1 diabetes to see how early intensive glucose control affects complications and quality of life over many years.
-
Role of THAP1 in brain cell support cells shaping brain development
Aims to understand how the THAP1 protein in oligodendrocyte lineage cells helps shape the brain’s environment and myelination during development, which may relate to a movement disorder called DYT6 dystonia.
-
New human monoclonal antibodies to stop malaria caused by Plasmodium vivax
A researcher team is developing human monoclonal antibodies to prevent and treat malaria from Plasmodium vivax, with a plan to test promising antibodies in primates and prepare for human trials.
-
PopCASE: A user-friendly tool to link cancer data for communities and researchers
Aimed at improving population cancer research, PopCASE helps connect patient cancer data with community information to inform better care and outreach.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.