Epidemiology of Diabetes Interventions and Complications (EDIC) Study follow-up
Official title: Epidemiology of Diabetes Interventions and Complications (EDIC) Study
Funded at Case Western Reserve University · NIH-11608533 · Data updated 2026-11-12
This long-term study follows adults with type 1 diabetes to see how early intensive glucose control affects complications and quality of life over many years.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | September 22, 2011 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $119,463 |
| NIH project number | 3U01DK094157-16S2 |
| Project ID | NIH-11608533 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with a history of type 1 diabetes who were part of the original DCCT/EDIC cohort and are willing to participate in ongoing follow-up.
✕Less likely to help
Patients not connected to the original DCCT/EDIC cohorts or those not engaging in long-term follow-up may not directly benefit.
What this research studies
The EDIC study continues the observational follow-up of participants from the DCCT trial to understand long-term outcomes of intensive glucose control on eye, kidney, nerve, cardiovascular, and overall health. Researchers collect standardized data on complications, risk factors, genetics, and quality of life to map how early treatment impacts later health. This information helps patients and clinicians understand the benefits and trade-offs of tight glycemic targets over time. Participation involves follow-up visits and data collection consistent with routine clinical monitoring. Findings aim to inform guidelines and empower patients with knowledge about long-term diabetes management.
Why it matters
Potential benefit: Understanding long-term effects of early intensive glucose control could improve future care strategies and reduce diabetes-related complications.
How similar studies have gone: Prior studies like DCCT/EDIC have demonstrated durable benefits of early intensive therapy, with ongoing follow-up providing deeper insights.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Gubitosi-Klug, Rose a — Case Western Reserve University
- Study coordinator: Gubitosi-Klug, Rose a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.