NIH-funded research R15 grant

Electromechanical reshaping of the cornea to adjust vision

Official title: The Electromechanical Reshaping of Cornea

Funded at Occidental College · NIH-11444584 · Data updated 2026-11-12

A patient-friendly look at a non-surgical approach that uses tiny electrical pulses to temporarily soften corneal tissue so it can be shaped for better vision.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionOccidental College
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startMay 1, 2021
Project endAugust 31, 2029
Funding year2026
Award (this year)$361,050
NIH project number2R15EY032273-02A1
Project IDNIH-11444584 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates may include individuals with refractive errors seeking non-surgical or less invasive correction options.

Less likely to help

People seeking immediate, proven surgical outcomes may not benefit until later-stage trials.

What this research studies

This grant explores a novel, non-ablative method called electromechanical reshaping (EMR) to subtly alter the cornea’s shape. Researchers will study how short electrical pulses cause chemical changes in the cornea’s collagen matrix, enabling safe mechanical remodeling without traditional surgery. The work builds on prior findings showing EMR can change corneal shape in ex vivo eyes, with aims to translate these ideas toward real patient treatments. If successful, this could provide a less invasive option for vision correction compared with LASIK or PRK.

Why it matters

Potential benefit: If successful, patients could have a less invasive way to correct refractive errors and reduce surgical risks.

How similar studies have gone: Preliminary ex vivo results suggest EMR can reshape corneal tissue, indicating potential but needing confirmation in living eyes.

Where this research is happening

  • Occidental College
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Hill, Michael G — Occidental College
  • Study coordinator: Hill, Michael G

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.