Dual-setting airway device to support heart attack survivors and after-resuscitation patients
Official title: A Dual-Setting Airway Device for Optimized Hemodynamics in Cardiac Arrest and Post-Resuscitation States
Funded at Resuscitation Innovations LLC · NIH-11406531 · Data updated 2026-11-12
A new adjustable breathing aid device helps improve blood flow and brain protection during and after cardiac arrest, aiming to increase survival with good brain function.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Resuscitation Innovations LLC NIH-funded |
| Lab location | 1 site (Minneapolis, UNITED STATES) |
| Project start | August 10, 2026 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $396,098 |
| NIH project number | 1R43HL186922-01 |
| Project ID | NIH-11406531 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include adults experiencing or at risk of cardiac arrest and post-resuscitation patients managed in emergency or critical care settings.
✕Less likely to help
Patients with conditions that contraindicate airway devices or those not at risk of cardiac arrest or post-resuscitation instability may not benefit.
What this research studies
This grant supports testing an innovative airway device that can be used during emergency resuscitation and after return of spontaneous circulation. The device, AP EC, is designed to offer two selectable pressures to optimize blood flow and reduce breathing work across different patient states. The project will evaluate safety and how well the device works in real-life resuscitation conditions, with measurements focused on hemodynamics and neurological outcomes. If successful, it could change how first responders and hospital teams support patients during and after cardiac arrest.
Why it matters
Potential benefit: If successful, the device could improve survival with better neurological outcomes after cardiac arrest.
How similar studies have gone: Prior use of head-up CPR with impedance devices showed improved outcomes when used with compatible settings, suggesting potential benefit for the dual-pressure approach.
Where this research is happening
-
Resuscitation Innovations LLC
Minneapolis, United States Active
Researchers
- Principal investigator: Lurie, Keith — Resuscitation Innovations LLC
- Study coordinator: Lurie, Keith
Related research
Other NIH-funded projects on the same topics.
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Multi-center study on how ventilation during CPR relates to cardiac arrest outcomes
A large, real-world study will look at how ventilation during CPR affects survival after out-of-hospital cardiac arrest in adults.
-
Specialized post-arrest care after cardiac arrest
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Platelet markers and blood flow to predict recurrent stroke in intracranial artery disease
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-
Reduce bias in predicting brain recovery after cardiac arrest
This project aims to make brain-recovery predictions more accurate for people who survive cardiac arrest by comparing outcomes between the United States and Brazil.
-
Fairer brain recovery predictions after cardiac arrest through U.S.–Brazil collaboration
This project aims to find better ways to predict brain recovery for people who survive cardiac arrest but have possible brain injury.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.