NIH-funded research R01 grant

DTTC-Connect: Helping kids with speech bring phrases to life

Official title: A randomized control trial of motor-based intervention for childhood apraxia of speech

Funded at New York University · NIH-11364832 · Data updated 2026-11-12

A child-focused trial tests a new DTTC-based method, DTTC-Connect, to improve connected speech in kids with childhood apraxia of speech.

More Speech research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University
NIH-funded
Lab location1 site (New York, United States)
Project startMay 20, 2020
Project endMarch 31, 2031
Funding year2026
Award (this year)$671,970
NIH project number2R01DC018581-06
Project IDNIH-11364832 on NIH RePORTER

Who could benefit from this research

Could help

Children with childhood apraxia of speech who are working on improving connected speech.

Less likely to help

Children with CAS who may not respond to this specific DTTC-Connect adaptation or who require different therapy approaches may not experience the same benefit.

What this research studies

This NIH grant funds a phase II randomized trial to see if DTTC-Connect can help children with childhood apraxia of speech say longer phrases more clearly, not just individual words. The study will compare the new DTTC-Connect approach to standard DTTC in a controlled way and track changes in speech motor control during connected speech. Researchers will measure phrase accuracy and how the mouth and throat move during natural speaking to understand the intervention’s impact on real-life communication. The goal is to help kids communicate more effectively in everyday conversations and participate more fully in school and social activities.

Why it matters

Potential benefit: If successful, children with CAS could have clearer and more confident everyday communication.

How similar studies have gone: Previous work showed word-level gains and reduced movement variability, suggesting potential for broader improvements with phrase-level practice.

Where this research is happening

  • New York University
    New York, United States
    Active

Researchers

  • Principal investigator: Grigos, Maria Irene — New York University
  • Study coordinator: Grigos, Maria Irene

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.