NIH-funded research Sbir 2 grant

DoseRT: A non-contact system to verify radiotherapy in real time

Official title: DoseRT™ : A Non-Contact Optical Patient and Beam Dosimetry System for Continuous in vivo Radiotherapy Verification

Funded at Doseoptics, LLC · NIH-11337506 · Data updated 2026-11-12

A non-contact optical system helps ensure precise radiation delivery to cancer patients during treatment.

More Radiotherapy research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionDoseoptics, LLC
NIH-funded
Lab location1 site (Lebanon, United States)
Project startAugust 1, 2018
Project endMay 31, 2027
Funding year2026
Award (this year)$998,974
NIH project number5R44CA232879-06
Project IDNIH-11337506 on NIH RePORTER

Who could benefit from this research

Could help

Adults undergoing external beam radiotherapy for cancer who would benefit from improved treatment verification.

Less likely to help

Patients not receiving external beam radiotherapy or those in clinics unable to adopt the imaging technology may not benefit.

What this research studies

This project develops BeamSite, a real-time optical imaging tool that visualizes how radiation is delivered to a patient during every treatment session. It uses Cherenkov imaging to provide time-gated feedback so clinicians can spot and correct small misalignments that could affect normal tissue or tumor dose. By giving immediate verification of beam placement, it aims to reduce daily human errors in radiotherapy care. The system is designed to integrate into busy clinics without adding significant workflow burdens.

Why it matters

Potential benefit: If successful, patients could receive more accurate radiation doses with potentially fewer side effects and lower risk of secondary cancers.

How similar studies have gone: Prior studies show that real-time imaging can improve accuracy, and this approach builds on existing Cherenkov imaging methods.

Where this research is happening

  • Doseoptics, LLC
    Lebanon, United States
    Active

Researchers

  • Principal investigator: Ware, William — Doseoptics, LLC
  • Study coordinator: Ware, William

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.