Developing safe imaging agents for better visibility in medical imaging
Official title: Biocompatible fluorophores for shortwave infrared imaging
Funded at University of California Los Angeles · NIH-10928166 · Data updated 2026-11-12
This study is working on new safe dyes that help doctors see tissues better during imaging tests, which could lead to improved diagnosis and treatment for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 13, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $374,481 |
| NIH project number | 5R01EB027172-06 |
| Project ID | NIH-10928166 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals undergoing procedures that require advanced imaging techniques, particularly in oncology or other conditions where tissue visibility is crucial.
✕Less likely to help
Patients who are not undergoing imaging procedures or those with conditions that do not require enhanced imaging techniques may not benefit from this research.
What this research studies
This research focuses on creating biocompatible contrast agents that enhance imaging capabilities in the shortwave infrared (SWIR) spectrum. By improving the visibility of tissues during imaging, the study aims to facilitate non-invasive multicolor imaging in animal models, which could lead to better diagnostics and treatment evaluations. The researchers will utilize their expertise in polymethine fluorophores to develop these agents, ensuring they are safe for biological use. This work could significantly improve the accuracy of imaging techniques used in clinical settings.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and safer imaging techniques for diagnosing and monitoring various medical conditions.
How similar studies have gone: Previous research has shown promise in using shortwave infrared imaging techniques, indicating that this approach has potential for success.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Sletten, Ellen May — University of California Los Angeles
- Study coordinator: Sletten, Ellen May
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.