Developing open-source systems for nerve stimulation and recording

HORNET Center for Autonomic Nerve Recording and Stimulation Systems (CARSS)

NIH-funded research University of Southern California · NIH-10908475

This study is working on new, flexible devices that can help stimulate and record signals from your nerves, making it easier for doctors to customize treatments for different health needs.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-10908475 on NIH RePORTER

What this research studies

This research focuses on creating open-architecture and open-source implantable systems designed for autonomic nerve stimulation and recording. By addressing the current limitations of existing closed-loop systems, the project aims to develop a customizable implantable pulse generator (IPG) and external charger that can be tailored for various clinical applications. The approach includes designing printed circuit board assemblies (PCBA) and firmware that can interface with different sensing and stimulation leads, facilitating more accessible clinical research in bioelectronic medicine. The developed systems will undergo benchtop testing to ensure their functionality and effectiveness.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals requiring neuromodulation therapies for conditions related to autonomic nerve dysfunction.

Not a fit: Patients who do not have conditions that affect the autonomic nervous system may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide patients with access to advanced neuromodulation therapies that are more adaptable to their specific medical needs.

How similar studies have performed: Other research has shown success with similar open-source approaches in medical technology, indicating potential for this novel application.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.