Developing an open-source system for autonomic nerve stimulation and recording
HORNET Center for Autonomic Nerve Recording and Stimulation Systems (CARSS)
This study is working on a new, easy-to-use system that helps doctors stimulate and monitor nerves in the body, making it easier for researchers to explore new treatments for conditions related to nerve function.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10908470 on NIH RePORTER |
What this research studies
This research aims to create an innovative open-architecture and open-source implantable system designed for autonomic nerve stimulation and recording. By addressing the current limitations of existing closed-loop systems, the project will provide researchers with the necessary tools to conduct clinical studies in bioelectronic medicine. The CARSS system will include components such as an external charger, controller, and various implantable leads, allowing for seamless integration and functionality. This approach aims to overcome technical, regulatory, and financial barriers faced by clinical researchers in accessing neuromodulation technologies.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals suffering from conditions that affect the autonomic nervous system, such as heart disease, diabetes, or chronic pain.
Not a fit: Patients with conditions unrelated to autonomic nerve function or those who do not require neuromodulation therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance the ability to study and treat conditions related to autonomic nerve dysfunction through advanced bioelectronic medicine applications.
How similar studies have performed: While there have been successful implementations of closed-loop neuromodulation systems, this open-source approach is relatively novel and aims to fill a significant gap in the current technology landscape.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Meng, Ellis — University of Southern California
- Study coordinator: Meng, Ellis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.