Developing open-source systems for nerve stimulation and recording

HORNET Center for Autonomic Nerve Recording and Stimulation Systems (CARSS)

NIH-funded research University of Southern California · NIH-10908473

This study is working on new, flexible devices that can help stimulate and monitor nerves in the body, aiming to improve treatments for conditions that need nerve therapy, so patients can have better options for managing their health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-10908473 on NIH RePORTER

What this research studies

This research focuses on creating flexible and customizable implantable systems for autonomic nerve stimulation and recording. By addressing the current limitations of existing closed-loop systems, the project aims to develop an open-architecture platform that allows for various clinical applications. Patients may benefit from these advancements as they could lead to improved treatments for conditions requiring neuromodulation. The approach includes designing mechanical modules for an implantable pulse generator and external charger, which will undergo rigorous testing.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with conditions that could benefit from autonomic nerve stimulation, such as chronic pain or gastrointestinal disorders.

Not a fit: Patients who do not have conditions related to autonomic nerve dysfunction may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide patients with access to more effective and customizable neuromodulation therapies.

How similar studies have performed: Other research in bioelectronic medicine has shown promise, but this approach of developing open-source systems is relatively novel.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.