Developing a new method to detect cancer biomarkers using nanosensor arrays
Official title: High-throughput, purification-free, and ultrasensitive transmembrane nanosensor arrays for digital counting of microRNA biomarkers of intact exosomes
Funded at Arizona State University-Tempe Campus · NIH-11081702 · Data updated 2026-11-12
This study is testing a new, easy way to check for cancer by using tiny sensors that can find specific markers in small samples of body fluids, so patients can avoid the hassle and risks of surgery for biopsies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Tempe, United States) |
| Project start | May 15, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $220,193 |
| NIH project number | 5R61CA278558-03 |
| Project ID | NIH-11081702 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals undergoing evaluation for cancer or those with a known cancer diagnosis who require monitoring.
✕Less likely to help
Patients who are not diagnosed with cancer or those who are not undergoing any cancer treatment may not benefit from this research.
What this research studies
This research focuses on creating advanced nanosensor arrays that can detect microRNA biomarkers found in exosomes, which are tiny vesicles released by cells. By using a non-invasive approach, this method aims to provide a quicker and more efficient way to diagnose and monitor cancer without the need for surgical biopsies. The technology is designed to be highly sensitive and specific, allowing for the detection of cancer progression through simple body fluid samples. This could significantly reduce the complications and costs associated with traditional biopsy methods.
Why it matters
Potential benefit: If successful, this research could lead to a revolutionary non-invasive diagnostic tool for cancer detection and monitoring.
How similar studies have gone: Previous research has shown promise in using liquid biopsies for cancer detection, but this approach with nanosensor arrays is relatively novel.
Where this research is happening
-
Arizona State University-Tempe Campus
Tempe, United States Active
Researchers
- Principal investigator: Yan, Hao — Arizona State University-Tempe Campus
- Study coordinator: Yan, Hao
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.