Developing a new method for sequencing proteins accurately
Official title: Nanopores for Processing Proteins
Funded at Electronic Biosciences, INC. · NIH-10645984 · Data updated 2026-11-12
This study is working on a new tool that can read and analyze proteins one at a time, which could help doctors better understand diseases and improve how they diagnose and treat patients.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Electronic Biosciences, INC. NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | September 20, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $407,291 |
| NIH project number | 1R43HG012961-01 |
| Project ID | NIH-10645984 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals with conditions that involve protein abnormalities or require precise biomarker identification.
✕Less likely to help
Patients with conditions unrelated to protein sequencing or those who do not require detailed protein analysis may not benefit from this research.
What this research studies
This research focuses on creating a novel nanopore reader that can sequence proteins at a single-molecule level with high accuracy. By utilizing advanced technology, the project aims to overcome the limitations of current protein sequencing methods, which are often expensive and lack the necessary sensitivity and accuracy. Patients may benefit from this research as it could lead to better understanding and profiling of proteins related to various diseases, enabling more precise diagnostics and treatment options. The methodology involves developing a sensor that can analyze individual proteins and detect specific modifications, which are crucial for understanding disease progression.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in protein sequencing, improving disease diagnosis and treatment strategies.
How similar studies have gone: While the approach of using nanopore technology for protein sequencing is innovative, similar technologies have shown promise in other areas of molecular biology, indicating potential for success.
Where this research is happening
-
Electronic Biosciences, INC.
San Diego, United States Active
Researchers
- Principal investigator: Ervin, Eric — Electronic Biosciences, INC.
- Study coordinator: Ervin, Eric
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.