NIH-funded research Sbir 2 grant

Detecting Absence Seizures in Kids at Home with a Mobile Recorder

Official title: Detecting Absence Seizures Using Hyperventilation In a Home Environment

Funded at Eysz, INC. · NIH-11584327 · Data updated 2026-11-12

A new mobile app helps doctors remotely diagnose and monitor childhood absence epilepsy using guided hyperventilation and video analysis to speed up treatment.

More Seizures research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionEysz, INC.
NIH-funded
Lab location1 site (Berkeley, UNITED STATES)
Project startSeptember 26, 2025
Project endJuly 31, 2028
Funding year2026
Award (this year)$1,591,774
NIH project number4R44NR021881-02
Project IDNIH-11584327 on NIH RePORTER

Who could benefit from this research

Could help

Children aged 0-11 years diagnosed with childhood absence epilepsy or suspected absence seizures and their caregivers.

Less likely to help

This approach may not benefit children whose seizures are not predominantly absence seizures or who cannot safely perform HV under supervision.

What this research studies

This project utilizes the Eysz HV Recorder app to capture video during a guided breathing exercise in children with absence epilepsy. Clinicians will analyze the video recordings to identify seizures and monitor response to treatment, aiming to speed up time to seizure freedom. The app currently works in clinics and is being studied further to improve accuracy and safe use in home settings. Families would participate by using the app under supervision to collect data during routine care.

Why it matters

Potential benefit: If successful, the approach could shorten the time to effective treatment and reduce seizure burden for children with CAE.

How similar studies have gone: Preliminary results show high sensitivity and good specificity for seizure detection using video analyses, suggesting potential for broader use.

Where this research is happening

  • Eysz, INC.
    Berkeley, United States
    Active

Researchers

  • Principal investigator: Kuperman, Rachel — Eysz, INC.
  • Study coordinator: Kuperman, Rachel

Related research

Other NIH-funded projects on the same topics.

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  • Gene editing therapies to prevent epileptic seizures

    A new gene-editing approach aims to reduce seizures in people with epilepsy by directly modifying a brain gene tied to the condition.

    NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11605225

  • Seizures and long-term outcomes after childhood stroke

    This project looks at whether early seizures and inflammation after a childhood stroke are linked to later epilepsy and recovery in kids up to 19 years old.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11474008

  • Using the brain’s natural connector to detect and prevent seizures

    A study at Case Western Reserve University is exploring whether gently stimulating a natural brain pathway called the corpus callosum can help identify where seizures start and stop them from spreading in people with hard-to-control epilepsy.

    NIH research Case Western Reserve University · Cleveland, United States · NIH-11449578

  • Disentangling How Inhibitory Brain Cells Shape Seizures in People

    This NIH grant tests how specific brain cells that normally calm the brain influence seizures in adults, using advanced optical methods in living subjects.

    NIH research Baylor College of Medicine · Houston, United States · NIH-11448856

  • Defining the brain regions that trigger seizures in epilepsy

    Researchers are studying which parts of the brain cause seizures in people with epilepsy to guide safer, more effective epilepsy surgery.

    NIH research University of California Los Angeles · Los Angeles, United States · NIH-11447901

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.