Cue-driven craving monitor for opioid use disorder using brain signals
Official title: Cue-induced drug craving monitoring for opioid use disorder with visual evoked potentials
Funded at Neurotype INC. · NIH-11360372 · Data updated 2026-11-12
A patient-friendly device and software combo will measure brain responses to opioid cues to help manage craving in people with opioid use disorder.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Neurotype INC. NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | September 30, 2023 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $870,345 |
| NIH project number | 4R44DA059517-02 |
| Project ID | NIH-11360372 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with opioid use disorder who are receiving treatment and may benefit from craving monitoring.
✕Less likely to help
Individuals without OUD or those not interested in brain-based monitoring may not benefit.
What this research studies
This project aims to develop and test a regulated device that can objectively monitor cue-induced craving in people with opioid use disorder by linking portable EEG readings to patterns in the brain. It uses NeuromarkR software to translate brain responses from opioid cues into a CIC-NAP biomarker, with plans to test usability and safety in real-world clinical settings. If successful, the device could help clinicians track craving signals and tailor treatment as part of standard OUD care. The program spans initial device integration, bench testing, and later clinical trials to link brain markers with treatment outcomes.
Why it matters
Potential benefit: If successful, it could provide an objective tool to predict relapse risk and guide personalized treatment for OUD.
How similar studies have gone: Early groundwork in brain-based craving monitoring shows potential, but translation to a practical CIC biomarker is still undergoing clinical testing.
Where this research is happening
-
Neurotype INC.
Minneapolis, United States Active
Researchers
- Principal investigator: Burwell, Scott — Neurotype INC.
- Study coordinator: Burwell, Scott
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.