Creating advanced fluorescent markers for detailed cellular imaging
Official title: Developing Switchable and Functional Fluorophores For Multi-Functional Super-Resolution Microscopy
Funded at North Carolina State University Raleigh · NIH-10940668 · Data updated 2026-11-12
This study is working on new tools that can light up and change how we see tiny parts of cells, helping us understand how they work together, which could lead to important discoveries for medical treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project start | September 15, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $364,969 |
| NIH project number | 1R35GM155241-01 |
| Project ID | NIH-10940668 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions related to cellular dysfunction or diseases where cellular interactions play a critical role.
✕Less likely to help
Patients with conditions that do not involve cellular or molecular interactions may not receive direct benefits from this research.
What this research studies
This research focuses on developing innovative fluorescent markers that can switch functions and provide detailed insights into cellular processes at the molecular level. By integrating these markers with advanced imaging techniques, the project aims to visualize and understand how individual biomolecules interact within their environments. This could lead to breakthroughs in understanding complex biological systems and cellular functions, which are crucial for various medical applications. The approach combines biophysics, biochemistry, and engineering to enhance the capabilities of super-resolution microscopy.
Why it matters
Potential benefit: If successful, this research could significantly improve our understanding of cellular functions and disease mechanisms, leading to better diagnostic and therapeutic strategies.
How similar studies have gone: Other research has shown success in using advanced imaging techniques to study cellular processes, indicating that this approach has the potential for significant breakthroughs.
Where this research is happening
-
North Carolina State University Raleigh
Raleigh, United States Active
Researchers
- Principal investigator: Zhang, Yang — North Carolina State University Raleigh
- Study coordinator: Zhang, Yang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.