Creating a knowledgebase for osteoarthritis research

The OAI Collaborative Osteoarthritis Research Enterprise (OAI CORE) Knowledgebase

NIH-funded research Univ of Massachusetts Med Sch Worcester · NIH-11015984

This study is creating a helpful resource that brings together important information about knee osteoarthritis from nearly 4,800 people, making it easier for researchers to find and use this data to improve treatments and care for the condition.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of Massachusetts Med Sch Worcester NIH-funded
Lab location1 site (Worcester, United States)
Project IDNIH-11015984 on NIH RePORTER

What this research studies

This research aims to develop a comprehensive knowledgebase that organizes and links extensive data related to the Osteoarthritis Initiative (OAI), which includes clinical data, medical images, and genetic information from nearly 4,800 individuals with or at risk for knee osteoarthritis. By centralizing this information, the project seeks to enhance the accessibility and utilization of OAI resources for researchers, ultimately accelerating discoveries in osteoarthritis treatment and management. The knowledgebase will employ modern technology and best practices to ensure high-quality data governance and support for the research community.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with knee osteoarthritis or those at risk of developing it.

Not a fit: Patients with osteoarthritis in joints other than the knee may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the understanding and treatment of osteoarthritis, leading to better patient outcomes.

How similar studies have performed: Previous research utilizing centralized databases for osteoarthritis has shown promise, indicating that this approach could be effective.

Where this research is happening

Worcester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.