Creating a comprehensive knowledge system for Alzheimer's disease
Official title: Construction and Application of Comprehensive Knowledge Graphs for Alzheimer's Disease
Funded at Univ of North Carolina Chapel Hill · NIH-10807706 · Data updated 2026-11-12
This study is working on creating a helpful tool that brings together different types of information about Alzheimer's disease to better understand it, which could lead to more personalized treatments for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | September 30, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $1,283,911 |
| NIH project number | 1R01AG085581-01 |
| Project ID | NIH-10807706 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias, as well as those at risk for these conditions.
✕Less likely to help
Patients with early-onset Alzheimer's or those without any cognitive impairment may not receive direct benefits from this research.
What this research studies
This research aims to develop a comprehensive knowledge graph specifically for Alzheimer's disease and related dementias. By integrating diverse data sources, including genetics, imaging, and clinical information, the project seeks to create a dynamic platform that can better understand the complex mechanisms behind Alzheimer's. The approach involves harmonizing data from various studies to address gaps and biases in current research. Patients may benefit from improved insights into their condition and more personalized treatment options as a result of this work.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment strategies for Alzheimer's disease and related dementias.
How similar studies have gone: Previous research utilizing knowledge graphs in other fields has shown promising results, indicating potential for success in this novel application for Alzheimer's disease.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Zhu, Hongtu — Univ of North Carolina Chapel Hill
- Study coordinator: Zhu, Hongtu
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.