Creating a complex molecule called dodecahedrane using innovative chemical methods.
Official title: Total Synthesis of Dodecahedrane via Carbon–Carbon Bond Forming Cascades
Funded at University of California Los Angeles · NIH-10848238 · Data updated 2026-11-12
This study is exploring new ways to create a complex molecule called dodecahedrane, which could help scientists develop better medicines for patients in the future.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $43,860 |
| NIH project number | 5F31GM148017-02 |
| Project ID | NIH-10848238 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research are individuals with conditions that could be treated by new drugs developed from the findings of this research.
✕Less likely to help
Patients with conditions that are not addressed by the types of drugs being synthesized may not receive any benefit from this research.
What this research studies
This research focuses on the total synthesis of dodecahedrane, a complex molecule, through advanced chemical techniques. The project employs carbon-carbon bond forming cascades to develop new methods for synthesizing small molecules, which are crucial for drug development and understanding chemical reactivity. The research involves preparing specific molecular scaffolds and utilizing unique reactions to assemble the target molecule. Patients may benefit indirectly from this work as it could lead to new pharmaceuticals and improved drug synthesis methods.
Why it matters
Potential benefit: If successful, this research could lead to the development of new drugs and improved methods for synthesizing important pharmaceutical compounds.
How similar studies have gone: Other research in the field of organic synthesis has shown success in developing new methods for drug synthesis, indicating that this approach has potential.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Mcdermott Catena, Luca — University of California Los Angeles
- Study coordinator: Mcdermott Catena, Luca
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.