NIH-funded research R01 grant

Cortical ways we plan speech in healthy people and Parkinson’s

Official title: Cortical mechanisms of normal and disordered human speech

Funded at New York University School of Medicine · NIH-11391876 · Data updated 2026-11-12

Researchers are studying how the brain plans speech in people with and without Parkinson’s disease to understand why speech may be harder for some individuals.

More Speech research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine
NIH-funded
Lab location1 site (New York, United States)
Project startJuly 1, 2026
Project endApril 30, 2031
Funding year2026
Award (this year)$685,327
NIH project number1R01DC023790-01
Project IDNIH-11391876 on NIH RePORTER

Who could benefit from this research

Could help

Adults with Parkinson’s disease and adults without PD who are part of prior or ongoing ECoG research or observational studies.

Less likely to help

The study involves invasive brain recordings in a subset of patients, which may not benefit all participants.

What this research studies

A team of neurosurgeons and brain scientists will study the brain activity related to speech planning using data from people with and without Parkinson’s disease. They will look at how large brain networks and local regions coordinate during spoken interactions and how this changes in PD. The project builds on previous work that used brain recordings and stimulation to identify speech-planning regions. Advanced analysis will track how brain signals evolve during the planning process in both groups. The goal is to reveal how PD might disrupt normal speech planning and how these networks behave at rest and during conversation.

Why it matters

Potential benefit: If successful, this research could improve our understanding of speech problems in PD and guide new approaches to therapy or interventions to support communication.

How similar studies have gone: Previous work has shown distinct planning networks and that perturbations can disrupt speech planning, supporting the approach as promising.

Where this research is happening

  • New York University School of Medicine
    New York, United States
    Active

Researchers

  • Principal investigator: Long, Michael a — New York University School of Medicine
  • Study coordinator: Long, Michael a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.