NIH-funded research P01 program project

Core C: A central hub to advance heart research

Official title: Core C

Funded at Temple Univ of the Commonwealth · NIH-11387606 · Data updated 2026-11-12

A core facility at Temple University helps multiple heart studies share resources and expertise to better understand how exosomes influence heart injury and protection.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionTemple Univ of the Commonwealth
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startSeptember 1, 2017
Project endJune 30, 2029
Funding year2026
Award (this year)$388,606
NIH project number5P01HL134608-08
Project IDNIH-11387606 on NIH RePORTER

Who could benefit from this research

Could help

Patients with cardiac diseases who may benefit from advances in understanding heart injury and protective mechanisms could indirectly benefit from the research.

Less likely to help

Patients not connected to the specific projects or not currently involved in related studies might not directly benefit.

What this research studies

This grant funds a Core C that provides specialized surgical and physiological services to several heart research projects. It aims to reduce variability in surgical techniques, improve experimental design, and help interpret data so findings can be more easily compared across studies. Researchers can rely on this core for consistent procedures, resource prioritization, and cross-project collaboration as the program progresses. The goal is to uncover how exosomes mediate cell-to-cell signaling within the heart and between organs, potentially guiding new strategies to protect the heart from injury.

Why it matters

Potential benefit: If successful, this core could accelerate discoveries about heart disease mechanisms and pave the way for better, more targeted therapies.

How similar studies have gone: Previous joint cores have improved collaboration and data consistency across projects, supporting progress in complex organ-system research.

Where this research is happening

  • Temple Univ of the Commonwealth
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Elrod, John William — Temple Univ of the Commonwealth
  • Study coordinator: Elrod, John William

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.