Consortium improving care for eosinophilic gastrointestinal diseases
Official title: Consortium of Eosinophilic Gastrointestinal Disease Researchers
Funded at Cincinnati Childrens Hosp Med Ctr · NIH-11464389 · Data updated 2026-11-12
A network of clinics is working together to advance care for adults with rare eosinophilic gut diseases like eosinophilic gastritis, enteritis, and colitis, with patient needs and trial readiness at the forefront.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project start | August 15, 2014 |
| Project end | July 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $1,715,911 |
| NIH project number | 2U54AI117804-11 |
| Project ID | NIH-11464389 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+ years) with eosinophilic gastritis, enteritis, or colitis who seek collaborative, translational research participation.
✕Less likely to help
Individuals without these specific EGID conditions or not enrolled in clinical-trial-ready research may not directly benefit.
What this research studies
CEGIR is a nationwide, multi-center effort that brings together adult patients with eosinophilic GI diseases to build translational clinical research. The consortium emphasizes collaboration across specialties and sites, merging pediatric and adult perspectives to create unified care pathways. Through patient-centric research, CEGIR aims to prepare for future clinical trials and accelerate translation of findings into real-world treatment options. This grant supports continued collaboration, data sharing, and mentorship to sustain progress in understanding and managing these rare conditions.
Why it matters
Potential benefit: If successful, patients could see faster development of effective treatments and better-informed care strategies for eosinophilic GI diseases.
How similar studies have gone: Previous CEGIR collaborations have demonstrated productive multi-site clinical and translational work in EGID.
Where this research is happening
-
Cincinnati Childrens Hosp Med Ctr
Cincinnati, United States Active
Researchers
- Principal investigator: Rothenberg, Marc E. — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Rothenberg, Marc E.
Related research
Other NIH-funded projects on the same topics.
-
Accelerating Rheumatic Heart Disease Prevention in Uganda
A program to find people with rheumatic heart disease in Ugandan communities and give them preventive care close to home.
-
Enhanced surveillance network to track childhood vaccines and viral infections in kids
A nationwide pediatric surveillance network will closely watch how common viruses and vaccines affect children’s health, using standard protocols at hospital and ED sites.
-
Advancing CNS drug delivery through epigenetic tweaks
A medical research project aims to help people with lysosomal storage disorders by improving how treatments reach the brain.
-
Spina Bifida Registry for Better Clinic Care
A national registry project aims to improve care for people with spina bifida by collecting and sharing data from multidisciplinary clinics to guide evidence-based practices.
-
Hydroxyurea to help children with sickle cell anemia in Africa
A pediatric study tests hydroxyurea treatment for young children with sickle cell anemia in several African countries to see if it can reduce illness and improve health.
-
Hydroxyurea for Children with Sickle Cell in Africa
A pilot study tests hydroxyurea in young children with sickle cell disease across several African countries to see if it can reduce illness and hospital visits.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.