NIH-funded research U01 cooperative agreement

Enhanced surveillance network to track childhood vaccines and viral infections in kids

Official title: IP21-002 US Enhanced Surveillance Network to Assess Burden, Natural History, and Effectiveness of Vaccines to Prevent Enteric and Respiratory Viruses in Children

Funded at Cincinnati Childrens Hosp Med Ctr · NIH-11624109 · Data updated 2026-11-12

A nationwide pediatric surveillance network will closely watch how common viruses and vaccines affect children’s health, using standard protocols at hospital and ED sites.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionCincinnati Childrens Hosp Med Ctr
NIH-funded
Lab location1 site (Cincinnati, United States)
Project startSeptember 1, 2021
Project endAugust 31, 2027
Funding year2025
Award (this year)$150,000
NIH project number6U01IP001155-05M003
Project IDNIH-11624109 on NIH RePORTER

Who could benefit from this research

Could help

Children under 18 seeking care at participating pediatric hospitals, including those with AGE or ARI, and healthy controls.

Less likely to help

Children not enrolled at participating sites or those not meeting inclusion criteria may not benefit directly.

What this research studies

This project creates a network of US children’s hospitals to actively monitor gastroenteritis and respiratory infections in kids, including healthy controls, to understand how well vaccines work and their impact on public health. It will enroll patients in inpatient and emergency department settings and collect data on viruses like norovirus, rotavirus, influenza, RSV, and others. The effort will use standardized procedures to track illness burden, natural history, and vaccine effects over time. Findings will inform vaccine recommendations and help guide future prevention strategies for pediatric infectious diseases.

Why it matters

Potential benefit: If successful, the study could improve vaccine guidance and reduce illness burden for children.

How similar studies have gone: Previous active surveillance programs have provided actionable data on infections and vaccine impact, with evolving improvements over time.

Where this research is happening

  • Cincinnati Childrens Hosp Med Ctr
    Cincinnati, United States
    Active

Researchers

  • Principal investigator: Staat, Mary a — Cincinnati Childrens Hosp Med Ctr
  • Study coordinator: Staat, Mary a

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.