NIH-funded research NIH-funded research

Center for Addiction and Disease Risk Exacerbation (CADRE)

Official title: Center for Addiction and Disease Risk Exacerbation

Funded at Brown University · NIH-11400077 · Data updated 2026-11-12

A multidisciplinary center at Brown University studies how substance use affects chronic disease risk and outcomes in kids and young people, with plans to track people over time to develop targeted prevention and intervention strategies.

More Addiction research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrown University
NIH-funded
Lab location1 site (Providence, United States)
Project startAugust 1, 2019
Project endJuly 31, 2029
Funding year2026
Award (this year)$2,257,346
NIH project number5P20GM130414-08
Project IDNIH-11400077 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include children, adolescents, and young adults affected by or at risk for substance use and chronic disease, and those who smoke or use cannabis.

Less likely to help

Individuals without substance use exposure or at low risk for chronic disease progression may not directly benefit from the specific interventions studied.

What this research studies

This program supports early-career researchers to study how substances like alcohol and cannabis influence health over the long term, especially in children and youth. It builds a community of investigators, cores for administration and clinical labs, and a pipeline from initial funding to independent research. The goal is to uncover biopsychosocial pathways linking substance use to chronic disease so future prevention efforts can be tailored to diverse populations.

Why it matters

Potential benefit: If successful, findings could lead to smarter prevention and intervention programs that reduce health disparities related to substance use in young people.

How similar studies have gone: Past CADRE findings include a large body of peer-reviewed work and several investigators advancing to independent funding.

Where this research is happening

  • Brown University
    Providence, United States
    Active

Researchers

  • Principal investigator: Monti, Peter M. — Brown University
  • Study coordinator: Monti, Peter M.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.