NIH-funded research NIH-funded research

Careful comparison of inpatient rehab methods after traumatic brain injury

Official title: Comparing Treatment Approaches to Promote Inpatient Rehabilitation Effectiveness for Traumatic Brain Injury (CARE 4 TBI)

Funded at Ohio State University · NIH-11399079 · Data updated 2026-11-12

A large study will follow people with moderate to severe brain injury to see which inpatient rehab practices help them recover best.

More Brain Injury research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startSeptember 15, 2021
Project endAugust 31, 2028
Funding year2026
Award (this year)$1,742,326
NIH project number5UH3NS117844-06
Project IDNIH-11399079 on NIH RePORTER

Who could benefit from this research

Could help

Adults with moderate to severe traumatic brain injury undergoing inpatient rehabilitation.

Less likely to help

Persons with mild TBI or those not receiving inpatient rehab may not benefit from this study's findings.

What this research studies

This project will observe patients with moderate to severe TBI across multiple rehab settings to compare different inpatient rehabilitation practices in real-world care. By using electronic medical records and advanced statistics, it will identify which approaches lead to better physical, behavioral, and cognitive outcomes. The focus is on practical, timely insights that can guide clinicians, patients, and families in choosing effective rehab strategies. The study builds on the long-running TBI Model Systems to gather robust, real-world data over time.

Why it matters

Potential benefit: If successful, the findings could help hospitals choose rehab approaches that improve recovery and reduce complications for people with TBI.

How similar studies have gone: Previous large observational efforts have advanced understanding of rehab outcomes, with ongoing work improving methods and interpretation.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Bogner, Jennifer a — Ohio State University
  • Study coordinator: Bogner, Jennifer a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.