Cannabis Use, Brain Function, and HIV

Translational Studies of Cannabis Administration, Cognition, and the Endocannabinoid System in HIV

NIH-funded research University of California, San Diego · NIH-11046697

This research explores how cannabis use affects thinking, decision-making, and the body's natural cannabinoid system in people living with HIV.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11046697 on NIH RePORTER

What this research studies

Many people with HIV use cannabis, either for medical reasons or recreationally, but we don't fully understand its effects on their brain function and overall health. This project aims to clarify how cannabis interacts with HIV treatments and influences cognitive abilities like decision-making and attention. We want to learn if cannabis offers benefits, like reducing inflammation, or if it might lead to negative consequences in people with HIV. Understanding these interactions is important because HIV can affect brain regions that are also influenced by cannabis.

Who could benefit from this research

Good fit: Ideal candidates for related future studies would be individuals aged 21 or older who are living with HIV and use cannabis.

Not a fit: Patients who do not have HIV or do not use cannabis would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could help patients and doctors make more informed decisions about cannabis use in the context of HIV, potentially leading to better management of cognitive health.

How similar studies have performed: While cannabis is often recommended for HIV symptoms, the specific consequences and interactions with HIV treatments and the endocannabinoid system in people with HIV are still largely unclear.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.