NIH-funded research R01 grant

Cannabis use after trauma: how acute stress and fear affect cannabis outcomes

Official title: Cannabis use following trauma exposure: An observational study of the impact of acute stress and fear response on cannabis outcomes

Funded at Brown University · NIH-11374389 · Data updated 2026-11-12

This study observes adults after a traumatic event to understand how stress and fear during the early days to months after trauma influence cannabis use and related problems.

More Cannabis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrown University
NIH-funded
Lab location1 site (Providence, United States)
Project startAugust 15, 2022
Project endMay 31, 2027
Funding year2026
Award (this year)$636,346
NIH project number5R01DA054116-05
Project IDNIH-11374389 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 18-25 or older who have recently experienced a traumatic event and are seeking care in emergency or clinical settings.

Less likely to help

Individuals without recent trauma exposure or those not using cannabis may not directly benefit from this study.

What this research studies

The project follows people who recently experienced trauma to see how their acute stress and fear responses relate to cannabis use over time. Researchers will collect data in clinical settings and may use surveys, interviews, and possibly biosamples to track symptoms and cannabis-related outcomes. The goal is to understand how the immediate aftermath of trauma shapes cannabis use patterns and potential problems, so clinicians can better support patients during this critical period.

Why it matters

Potential benefit: If successful, it could help doctors tailor guidance and support for patients after trauma to reduce cannabis-related harms.

How similar studies have gone: Prior research shows links between trauma and cannabis use, but results are mixed and more detail on early post-trauma periods is needed.

Where this research is happening

  • Brown University
    Providence, United States
    Active

Researchers

  • Principal investigator: Nugent, Nicole R — Brown University
  • Study coordinator: Nugent, Nicole R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.