NIH-funded research U01 cooperative agreement

Body composition and outcomes after lung transplant

Official title: The impact of body composition on peri-operative and patient-centered outcomes in lung transplantation.

Funded at University of California, San Francisco · NIH-11386388 · Data updated 2026-11-12

This study explores how body composition affects recovery and patient-reported well-being after lung transplantation.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startAugust 5, 2022
Project endJuly 31, 2027
Funding year2026
Award (this year)$418,486
NIH project number5U01HL163242-05
Project IDNIH-11386388 on NIH RePORTER

Who could benefit from this research

Could help

Lung transplant candidates and recipients at participating centers, especially those with concerns about body composition.

Less likely to help

Patients not undergoing or considered for lung transplantation may not directly benefit.

What this research studies

If you or a loved one is considering lung transplantation, this project looks at how factors like body fat and muscle mass influence recovery after surgery and quality of life. Researchers will use body measurements and a technique called bioelectrical impedance to understand how obesity or muscle loss relate to complications and overall well-being. The goal is to identify patients at higher risk for poor outcomes so clinicians can tailor care before and after transplant. The findings could lead to better nutritional and rehabilitation strategies to improve survivorship and daily functioning.

Why it matters

Potential benefit: Potential to personalize pre- and post-transplant care to improve survival and quality of life.

How similar studies have gone: Previous work linked sarcopenia and obesity to complications; the study builds on that groundwork with advanced body-composition measures.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Singer, Jonathan Paul — University of California, San Francisco
  • Study coordinator: Singer, Jonathan Paul

Related research

Other NIH-funded projects on the same topics.

  • Body composition and outcomes after lung transplant

    A patient-focused look at how body fat and muscle measurements around the time of lung transplant relate to recovery, complications, and quality of life after surgery.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11585360

  • Advanced body fat imaging to improve lung transplant outcomes

    This project uses CT imaging of fat distribution to better predict who will do well with a lung transplant and when to list them, with the goal of improving survival after transplant.

    NIH research University of Pennsylvania · Philadelphia, United States · NIH-11398153

  • How body fat and muscle affect recovery after lung transplant

    This project looks at how body fat and muscle mass relate to recovery, complications, and quality of life for people getting lung transplants.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11383321

  • How body fat and muscle affect recovery and quality of life after lung transplant

    This research looks at whether body fat, muscle mass, and related body-measure tests predict complications, survival, and quality of life for people getting lung transplants.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11146424

  • How body composition affects outcomes in lung transplantation

    This study is looking at how body weight and muscle health affect recovery and quality of life for people getting a lung transplant, so we can better support patients during their healing process.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11144645

  • How body composition affects outcomes for lung transplant patients

    This study is looking at how body weight and muscle mass affect the health and recovery of people getting a lung transplant, with the goal of helping doctors better care for their patients.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-10899478

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.