NIH-funded research NIH-funded research

Biomarker Development Unit for cancer detection

Official title: Biomarker Developmental Unit

Funded at Arizona State University-Tempe Campus · NIH-11412529 · Data updated 2026-11-12

A patient-facing program to develop and validate blood biomarkers that could help detect lung and ovarian cancer early using accessible antibody-based tests.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus
NIH-funded
Lab location1 site (Scottsdale, United States)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$396,983
NIH project number5U2CCA271903-05
Project IDNIH-11412529 on NIH RePORTER

Who could benefit from this research

Could help

Individuals at risk for lung or ovarian cancer or those undergoing cancer screening who could contribute samples for assay validation.

Less likely to help

People without cancer or with non-cancerous conditions may not directly benefit from these tests.

What this research studies

This grant supports converting research-based antibody tests into clinically usable assays and participating in collaborative validation studies. It focuses on detecting early cancer signals through serological markers such as autoantibodies and antibodies against tumor proteins. The work is conducted through ASU's Biomarker Characterization Center in partnership with a diagnostics company to ensure the tests are practical for clinical use. By validating these assays on human samples, the project aims to improve early cancer detection options for patients.

Why it matters

Potential benefit: If successful, patients could benefit from earlier and more accurate cancer detection through blood tests.

How similar studies have gone: Previous biomarker validation efforts have shown that blood-based antibody markers can aid early cancer detection when properly validated.

Where this research is happening

  • Arizona State University-Tempe Campus
    Scottsdale, United States
    Active

Researchers

  • Principal investigator: Stengelin, Martin — Arizona State University-Tempe Campus
  • Study coordinator: Stengelin, Martin

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.