Improving understanding and management of eye diseases using biobank data
Biobank phenotyping tools for improved understanding and management of eye diseases and disparities
['FUNDING_R01'] · VANDERBILT UNIVERSITY MEDICAL CENTER · NIH-11171775
This study is looking at how your genes might be linked to eye diseases, especially for people of African descent, by combining genetic information with health records to help doctors better understand and manage these conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-11171775 on ClinicalTrials.gov |
What this research studies
This research aims to enhance our understanding of eye diseases by integrating genetic information with clinical data from electronic health records. By analyzing this combined data, researchers hope to uncover associations between genetic variants and various eye conditions, particularly those affecting individuals of African descent. The study will utilize advanced algorithms to create risk prediction models that can inform clinical management and identify new research avenues. This approach seeks to provide a more comprehensive view of eye health and disease mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of eye diseases, particularly those of African ancestry, as well as those diagnosed with age-related macular degeneration.
Not a fit: Patients without a genetic predisposition to eye diseases or those not of African descent may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnosis and management strategies for eye diseases, particularly for underserved populations.
How similar studies have performed: Previous research has successfully utilized biobank data to uncover genetic associations with various diseases, indicating a promising potential for this approach in eye health.
Where this research is happening
NASHVILLE, UNITED STATES
- VANDERBILT UNIVERSITY MEDICAL CENTER — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PADOVANI-CLAUDIO, DOLLY ANN — VANDERBILT UNIVERSITY MEDICAL CENTER
- Study coordinator: PADOVANI-CLAUDIO, DOLLY ANN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: age related macular disease